CBD Oil – Organic

What is CBD Oil?CBD Oil3

CBD

CBD short for Cannabidiol is a substance extracted from the hemp plant. The medical effects of CBD are significant. CBD does not produce any psychoactive effects like THC. People do not get a “stoned” feeling when using CBD oil. Our CBD Oil contains NO THC and therefore is Legal to sell and buy in the UK.

CBD medical oil

CBD oil can be used by all human beings of every age. Even infants and animals can use CBD oil safely for medical purposes. CBD oil has no known adverse side effects. Our CBD Oil is 100% natural and organic, no additives or preservatives are added and it’s Non GMO. The CBD extract is diluted with organic Hemp oil.

Alternative treatment

CBD oil is widely used as an alternative medical treatment by people who suffer from chronic pains, anxiety attacks, psychosis, inflammatory and/or spasm effects. This alternative treatment is often chosen by patients because there are no side effects as dysphoria (sad or irritable mood) or lethargy ( a sleep-like state in which the patient after he has awakened from his sleep state, falls back, chronic fatigue).

Percentage

There are many different percentages of CBD available.
The percentage (%) represents the amount of CBD Oil per 10ml bottle. Also expressed as ?mg

Our CBD products come in Colour Top Bottles for easy identification, complete with a Dropper to enable taking the Oil as easy as possible. Just stand in front of a mirror and count the number of drops you drip under your tongue. NOTE: The more concentrated CBD Oil the more you may need to warm it up in your hands or pocket first. Each Bottle contains an average of around 225-230 drops:

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Disorders and conditions

Studies, both scientific and clinical, show that CBD has astonishing effects when used for treatment of many neurological disorders and a wide range of diseases and conditions.

The most known treated disorders are:

  • Antibiotic-resistant infections
  • Immuno-suppressive
  • Rheumatoid arthritis
  • Psoriasis
  • PTSD
  • Anxiety attacks
  • Vascular and muscle relaxing
  • Diabetes
  • Alcoholism
  • Spasm
  • MS (Multiple Sclerosis)
  • Epilepsy
  • Chronic pain
  • schizophrenia

Neurogenic as well as neuroprotective effects has been demonstrated by CBD. The most famous story about CBD-rich cannabis effects in mainstream media is “Charlotte’s Web”. Several academic research centers across the world are investigating CBDs anti-cancer properties. The sounds are very promising about CBD-rich cannabis’ curative qualities.

 

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Beneficial effects of taking CBD Oil:

  • Pain relief
  • Suppressing appetite
  • Reducing vomiting & nausea
  • Reducing contractions in small intestine
  • Relieves anxiety
  • Tranquilizing, used to manage psychoses
  • Reduce seizures and convulsions
  • Suppresses muscle spasms
  • Increases efficacy of the immune system
  • Reduces blood sugar levels
  • Reduces nervous system degeneration
  • Treats psoriasis
  • Reduces risk of artery blockage
  • Kills or slows bacterial growth
  • Treats fungal infection
  • Inhibits cell growth in tumors/cancer cells
  • Promotes bone growth
  • Promotes brain tissue growth in alcoholism
  • Reduces nicotine craving

 

History

Cannabis has been used as a medicine for over 3,500 years with not one  recorded death related to it. Decades ago Cannabis was a legitimate medication prescribed by doctors and dispensed by pharmacies across the world. Made Illegal  in the 1930′s as it was considered to have no medicinal qualities and be highly addictive to users, worse still the media portrayed it as the devils drug and films such as “Reefer madness” scared people into thinking that it was dangerous which is still ingrained into society today as the truth is not yet public knowledge.

Now there is massive amounts of research available today to say that Cannabis is not only medicinal, but the greatest medicine of them all! www.endalldisease.com have compiled a list of medical studies from credible medical journals around the world which all have  a consistent theme between them, it is that “cannabis shrinks tumors and selectively targets cancer cells“.

The most common use for medical Cannabis is for pain. Scientists say it works by modulating the electrical and chemical activity to help reduce excessive activity. It binds to the receptors through out the brain and body, reduce inflamation and provide a buffer against pain, the receptors control movement, coordination, memory, learning, appetite, pleasure, sensation, sense of space and time and other drives.

Scientists in Israel are now reporting that Cannabis can actually protect the brain, and even decrease the amount of brain damage from head injuries, so you can give medicine after the injury to reverse some of the damage! The “Grandad of Cannabis research”  Dr Raphael Mechoulam claims, to get the best results you need Tetrahydrocannabinol present with Cannabidiol which he calls the entourage effect, but unfortunately for now THC remains illegal in this country.

Cannabinoids were first discovered in the 1940s, when CBD and CBN (cannabiniol) were identified. The structure of THC was first determined in 1964.

Due to molecular similarity and ease of synthetic conversion, CBD was originally believed to be a natural precursor to THC. However, it is now known that CBD and THC are produced independently in the cannabis plant from the precursor CBG

Cannabidiol (CDB)

CDB is one of at least 60 active cannabinoids identified in cannabis. It is a major constituent of the plant, accounting for up to 40% of the plant’s extract, as a non-psychotropic phytocannabinoid. CBD is considered to have a wider scope of medical applications than tetrahydrocannabinol (THC).

 Pharmacology

Cannabinoids can be administered by smoking, vaporizing, oral ingestion, transdermal patch, intravenous injection, sublingual absorption, or rectal suppository. Once in the body, most cannabinoids are metabolized in the liver

Cannabinoid receptors

Before the 1980s, it was often speculated that cannabinoids produced their physiological and behavioral effects via nonspecific interaction with cell membranes, instead of interacting with specific membrane-bound receptors. The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate. These receptors are common in animals, and have been found in mammals, birds, fish, and reptiles. At present, there are two known types of cannabinoid receptors, termed CB1 and CB2, with mounting evidence of more. The human brain has more cannabinoid receptors than any other G protein-coupled receptor (GPCR) type.

Cannabinoid receptor type 1

CB1 receptors are found primarily in the brain, more specifically in the basal ganglia and in the limbic system, including the hippocampus. They are also found in the cerebellum and in both male and female reproductive systems. CB1 receptors are absent in the medulla oblongata, the part of the brain stem responsible for respiratory and cardiovascular functions. Thus, there is not the risk of respiratory or cardiovascular failure that can be produced by some drugs. CB1 receptors appear to be responsible for the euphoric and anticonvulsive effects of cannabis.

Cannabinoid receptor type 2

CB2 receptors are predominantly found in the immune system, or immune-derived cells with the greatest density in the spleen. While found only in the peripheral nervous system, a report does indicate that CB2 is expressed by a subpopulation of microglia in the human cerebellum. CB2 receptors appear to be responsible for the anti-inflammatory and possibly other therapeutic effects of cannabis.

Some cannabidiol oil is derived from marijuana and therefore contains higher levels of THC. This type of cannabidiol oil would be considered a Schedule I as a result of the THC present.

US patent[edit]

In October 2003, U.S. patent #6630507 entitled “Cannabinoids as antioxidants and neuroprotectants” was assigned to “The United States Of America As Represented By The Department Of Health And Human Services.” The patent was filed in April 1999 and listed as the inventors: Aidan J. Hampson, Julius Axelrod, and Maurizio Grimaldi, who all held positions at the National Institute of Mental Health (NIMH) in Bethesda, MD, which is part of the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). The patent mentions cannabidiol’s ability as an antiepileptic, to lower intraocular pressure in the treatment of glaucoma, lack of toxicity or serious side effects in large acute doses, its neuroprotectant properties, its ability to prevent neurotoxicity mediated by NMDA, AMPA, or kainate receptors; its ability to attenuate glutamate toxicity, its ability to protect against cellular damage, its ability to protect brains from ischemic damage, its anxiolytic effect, and its superior antioxidant activity which can be used in the prophylaxis and treatment of oxidation associated diseases.

“ “Oxidative associated diseases include, without limitation, free radical associated diseases, such as ischemia, ischemic reperfusion injury, inflammatory diseases, systemic lupus erythematosus, myocardial ischemia or infarction, cerebrovascular accidents (such as a thromboembolic or hemorrhagic stroke) that can lead to ischemia or an infarct in the brain, operative ischemia, traumatic hemorrhage (for example a hypovolemic stroke that can lead to CNS hypoxia or anoxia), spinal cord trauma, Down’s syndrome, Crohn’s disease, autoimmune diseases (e.g. rheumatoid arthritis or diabetes), cataract formation, uveitis, emphysema, gastric ulcers, oxygen toxicity, neoplasia, undesired cellular apoptosis, radiation sickness, and others. The present invention is believed to be particularly beneficial in the treatment of oxidative associated diseases of the CNS, because of the ability of the cannabinoids to cross the blood brain barrier and exert their antioxidant effects in the brain. In particular embodiments, the pharmaceutical composition of the present invention is used for preventing, arresting, or treating neurological damage in Parkinson’s disease, Alzheimer’s disease and HIV dementia; autoimmune neurodegeneration of the type that can occur in encephalitis, and hypoxic or anoxic neuronal damage that can result from apnea, respiratory arrest or cardiac arrest, and anoxia caused by drowning, brain surgery or trauma (such as concussion or spinal cord shock).
On November 17, 2011, the Federal Register published that the National Institutes of Health of the United States Department of Health and Human Services was “contemplating the grant of an exclusive patent license to practice the invention embodied in U.S. Patent 6,630,507″ to the company KannaLife based in New York, for the development and sale of cannabinoid and cannabidiol based therapeutics for the treatment of hepatic encephalopathy in humans.

The following are some interesting events in the history of Medical Marijuana.

2000 BC: In Egypt, cannabis is used to treat sore eyes. [-1972 National Commission on Marihuana and Drug Abuse – Appendix, Chapter One, Part I ]

1400 BC: A thriving Bronze Age drug trade supplied hashish (cannabis) and opium to ancient cultures throughout the eastern Mediterranean as balm for the pain of childbirth and disease, proving a sophisticated knowledge of medicines dating back thousands of years. [-Aug. 8, 2002 Associated Press report of conference on DNA and archaeology in Israel.]

Pre 1000 BC: Cannabis use begins in India to overcome hunger and thirst by the religious mendicants. [-1972 National Commission on Marihuana and Drug Abuse – Appendix, Chapter One, Part I]

1000 BC: Bhang, a cannabis preparation (a drink, generally mixed with milk) is used as an anesthetic and anti-phlegmatic in India. Cannabis begins to be used in India to treat a wide variety of human maladies. The drug is still highly regarded and used by some medical practitioners in India. [-1972 National Commission on Marihuana and Drug Abuse – Appendix, Chapter One, Part I]

500 BC: Gautama Buddha is said to have survived by eating only cannabis seeds. [-2002 UK Cannabis Campaigners’ Guide]

200 BC: In ancient Greece, cannabis is used as a remedy for earache, edema, and inflammation. [-1972 National Commission on Marihuana and Drug Abuse – Appendix, Chapter One, Part I]

70 BC: Roman Emperor Nero’s surgeon, Dioscorides, praises cannabis for making the stoutest cords and for its medicinal properties. [-2002 UK Cannabis Campaigners’ Guide.]

200 AD: A Chinese physician, Hoa-Tho, prescribes cannabis as an analgesic in surgical procedures. [-1972 National Commission on Marihuana and Drug Abuse – Appendix, Chapter One, Part I.]

1621: The medical book The Anatomy of Melancholy by English clergyman Robert Burton claims cannabis is a treatment for depression. [-2002 UK Cannabis Campaigners’ Guide.]

pre-1700: Cannabis is used in Africa to restore appetite and to relieve pain of hemorrhoids. Its antiseptic uses are also known to certain African tribes. Various other uses, in a number of African countries, include the treatment of tetanus, hydrophobia, delirium tremens, infantile convulsions, neuralgia, cholera, menorrhagia, rheumatism, hay fever, asthma, skin diseases, and protracted labor during childbirth. [-1972 National Commission on Marihuana and Drug Abuse.]

1799: Napoleon’s army returns from Egypt with knowledge (and samples) of cannabis. The scientific members of Napoleons forces are interested in the drug™s pain relieving and sedative effects. [-1972 National Commission on Marihuana and Drug Abuse – Appendix, Chapter One, Part I.]

1839: William O’Shaughnessy, an Irishman working in the service of the British in India, writes the first modern English medical article on cannabis. [-1972 National Commission on Marihuana and Drug Abuse – Appendix, Chapter One, Part I.]

1842: Shaughnessy reports that tetanus could be arrested and cured when treated with extra large doses of cannabis. [-1972 National Commission on Marihuana and Drug Abuse – Appendix, Chapter One, Part I.] Various marijuana and hashish extracts are the first, second or third most prescribed medicines in the United States from 1842 until the 1890s. [-Nov. 2000 Jack Herer The Emperor Wears No Clothes.]

1854: The US Dispensary of 1854 lists cannabis compounds as suggested remedies for a multitude of medical problems, including neuralgia, depression, hemorrhage, pain relief and muscle spasm. [-1999 Saul Rubin Offbeat Marijuana.] 1857: Smith Brothers of Edinburgh market cannabis indica extracts. -[2002 UK Cannabis Campaigners’ Guide.]

1893-94: India establishes the India Hemp Commission to examine the question of cannabis use in India. The Commission reports the use of cannabis as an analgesic, a restorer of energy, a hemostat, an ecbolic, and an anti-diarrhetic. Cannabis is also mentioned in the report as an aid in treating hay fever, cholera, dysentery, gonorrhea, diabetes, impotence, urinary incontinence, testicular swelling, granulation of open sores, and chronic ulcers. Other beneficial effects attributed to cannabis are prevention of insomnia, relief of anxiety, protection against cholera, alleviation of hunger and as an aid to concentration of attention. [-1972 National Commission on Marihuana and Drug Abuse – Appendix, Chapter One, Part I.]

1898: Sir William Osler, professor of medicine at the Johns Hopkins and later Regius Professor of Medicine at the University of Oxford, stated in his 1898 discussion of migraine headaches that marijuana “is probably the most satisfactory remedy” for that condition. [-2002 The Schaffer Online Library of Drug Policy]

1947: Dr. Douthwaite reports using cannabis hashish “for reducing of anxiety and tension in patients with duodenal ulcer. [-1972 National Commission on Marihuana and Drug Abuse.]

1949: Researchers JP Davis and HH Ramsey report (Fed. Proc. Am. Soc. Exp. Biol. 8: 284) that a clinical trial of five institutionalized epileptic children found that: “Three children – responded at least as well as to previous therapy. Fourth child “ almost completely seizure free. Fifth child “ entirely seizure free. Their conclusion was that “the cannabinols herein reported deserve further trial in non-institutionalized epileptics. [-1972 National Commission on Marihuana and Drug Abuse.]

1952: Dr. J. Kapelikovi, in his report “Antibacterial Action of Cannabis Indica,” concludes that “alcohol extract of cannabis is bacterially effective against many gram-positive and one gram-negative micro-organisms.” He also found a paste form of external application successful. According to the report; “from a study of 2,000 herbs by Czechoslovakian scientists it was found that cannabis indica was the most promising in the realm of antibiotics. [-1972 National Commission on Marihuana and Drug Abuse.]

1957: Drs. Chopra and Chopra, in their article “The Use of the Cannabis Drugs in India, state; “with regard to the use of cannabis in Indian indigenous medicine at the present time, it may be said that it was and still is fairly extensively used in both the Ayurvedic (Hindu) and Tibb (Mohammedan) systems of medicine as an anodyne, hypnotic, analgesic and antispasmodic, and as a remedy for external application to piles. It is also used in the treatment of dysmennorhoea, rheumatism, chronic diarrhea of the sprue type, gonorrhea, malaria and mental diseases on the advice of itinerant practitioners of indigenous medicine as well as quacks who roam about the country. For medicinal purposes the drug is administered by mouth and hardly ever by smoking. [-1972 National Commission on Marihuana and Drug Abuse.]

1960: Krejci, Kabelik and Santavy include in “Cannabis as a medicine and the various microorganisms against which cannabis is effective; “Proof could be furnished that the cannabis extracts produce a very satisfactory antibacterial effect upon the following microbes: staphylococcus pyogenes aureus, streptococcus alpha haemolyticus, streptococcus beta haemolyticus, enterococcus, diplococcus pneumonia, B. antracis, and corynebacterium diptheriae i.e., all of them gram-positive microorganisms. Noteworthy is the effect upon staphyloccus aureaus strains, which are resistant to penicillin and to other antibiotics.” Kabelik reports that in Argentina “cannabis is considered a real panacea for tetanus, colic, gastralgia, swelling of the liver, gonorrhea, sterility, impotency, abortion, tuberculosis of the lungs and asthma,even the root-bark has been collected in spring, and employed as a fibrifuge, tonic, for treatment of dysentery and gastralgia, either pulverized or in form of decoctions. The root when ground and applied to burns is said to relieve pain. Oil from seeds has been frequently used even in treatment of cancer. Kabelik also notes; “In human therapy the best results have been obtained with the following medicaments combined with substances derived from cannabis: dusting powder together with boric acid, ointment, ear drops, alcohol solutions with glycerine, aqueous emulsions, dentin powder. The preparations mentioned above have been already tested clinically, and will eventually be made available for production. [-1972 National Commission on Marihuana and Drug Abuse.]

1971: Drs. Hepler and Frank report that cannabis reduces intraocular pressure by up to 30%, thus helping glaucoma patients. [-1972 National Commission on Marihuana and Drug Abuse.]

1975: Dr. Donald Tashkin et al publishes an article in American Review of Respiratory Disease (Volume 112, 1975) which, Dr. Tashkin says “appear to support the benefit ascribed to the use of cannabis in the last century for the treatment of bronchial asthma.”

2001: Canada is the first nation to allow patients to legally use medical marijuana.

2009: Nearly 4,000 patients have successfully enrolled in Canada’s MMAR program. – See more at: http://www.vimm.ca/legal/brief-history-of-the-medical-use-of-marijuana/#sthash.6DLtfix3.dpuf

 

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